EC 1 - Oxidoreductases
EC 1.3 - Acting on the CH-CH group of donors
EC 1.3.1 - With NAD+ or NADP+ as acceptor
EC 1.3.1.53 - (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 1.3.1.53
Names
Accepted name:
(3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase
Other
names:
(1R,2S)-dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylate dehydrogenase
dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylate dehydrogenase
cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,4-dicarboxylate:NAD+ oxidoreductase (decarboxylating)
DCD dehydrogenase
dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylate dehydrogenase
cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,4-dicarboxylate:NAD+ oxidoreductase (decarboxylating)
DCD dehydrogenase
Systematic name:
(3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate:NAD+ oxidoreductase
Reaction
- (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD+ = 3,4-dihydroxybenzoate + CO2 + NADH
Cofactor
Comments:
Requires FeII. Involved in the terephthalate degradation pathway in bacteria [2].
Links to other databases
Gene Ontology:
GO:0047120
CAS Registry Number:
162032-77-1
UniProtKB/Swiss-Prot:
References
-
Purification and some properties of (1R,2S)-dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylate dehydrogenase from Comamonas testosteroni T-2.FEMS Microbiol. Lett. 130 : 97-102 (1995).
-
Molecular analysis of isophthalate and terephthalate degradation by Comamonas testosteroni YZW-D.Environ. Health Perspect. 103 S : 9-12 (1995). [PMID: 8565920]
[EC 1.3.1.53 created 1999 (EC 1.3.1.61 created 2000, incorporated 2007)]