EC 1 - Oxidoreductases
EC 1.3 - Acting on the CH-CH group of donors
EC 1.3.1 - With NAD+ or NADP+ as acceptor
EC 1.3.1.38 - trans-2-enoyl-CoA reductase (NADPH)
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 1.3.1.38
Names
Accepted name:
trans-2-enoyl-CoA reductase (NADPH)
Other
names:
NADPH-dependent trans-2-enoyl-CoA reductase
reductase, trans-enoyl coenzyme A
reductase, trans-enoyl coenzyme A
Systematic name:
acyl-CoA:NADP+ trans-2-oxidoreductase
Reaction
-
33763 [IUBMB]+a (2E)-enoyl-CoAName origin: UniProt - CHECKED (C)Formula: C24H33N7O17P3SR
Charge: -4ChEBI compound status: CHECKED (C)+H+Name origin: UniProt - CHECKED (C)Formula: H
Charge: 1ChEBI compound status: CHECKED (C)NADPHName origin: UniProt - CHECKED (C)Formula: C21H26N7O17P3
Charge: -4ChEBI compound status: CHECKED (C)=+a 2,3-saturated acyl-CoAName origin: UniProt - CHECKED (C)Formula: C24H35N7O17P3SR
Charge: -4ChEBI compound status: CHECKED (C)
Comments:
Not identical with EC 1.3.1.37 cis-2-enoyl-CoA reductase (NADPH) [cf. EC 1.3.1.8 acyl-CoA dehydrogenase (NADP+)].
Links to other databases
Protein domains and families:
PROSITE:PDOC00060
Gene Ontology:
GO:0019166
CAS Registry Number:
77649-64-0
UniProtKB/Swiss-Prot:
PECR_CAVPO
PECR_HUMAN
PECR_MOUSE
PECR_PONAB
PECR_RAT
YN67_SCHPO
References
-
Studies on the metabolism of unsaturated fatty acids. IX. Stereochemical studies of the reaction catalyzed by trans-2-enoyl-coenzyme A reductase of Escherichia coli.J. Biochem. (Tokyo) 92: 1649-1654 (1982). [PMID: 6759504]
[EC 1.3.1.38 created 1986]