IntEnz

EC 1.3.1.31 - 2-enoate reductase

IntEnz Enzyme Nomenclature
EC 1.3.1.31

Names

Reaction

• 10200 [IUBMB]
  butanoate

  butanoate

  Name origin: UniProt - CHECKED (C)

  CHEBI:17968

  Formula: C4H7O2
  Charge: -1

  ChEBI compound status: CHECKED (C)

  

  +

  NAD⁺

  NAD(+)

  Name origin: UniProt - CHECKED (C)

  CHEBI:57540

  Formula: C21H26N7O14P2
  Charge: -1

  ChEBI compound status: CHECKED (C)

  

  =

  (2E)-2-butenoate

  (2E)-2-butenoate

  Name origin: UniProt - CHECKED (C)

  CHEBI:35899

  Formula: C4H5O2
  Charge: -1

  ChEBI compound status: CHECKED (C)

  

  +

  H⁺

  H(+)

  Name origin: UniProt - CHECKED (C)

  CHEBI:15378

  Formula: H
  Charge: 1

  ChEBI compound status: CHECKED (C)

  

  +

  NADH

  NADH

  Name origin: UniProt - CHECKED (C)

  CHEBI:57945

  Formula: C21H27N7O14P2
  Charge: -2

  ChEBI compound status: CHECKED (C)

  

Cofactors

• iron-sulfur
• FAD

Comments:

An iron-sulfur-flavoprotein (FAD). Acts (in the reverse direction) on a wide range of alkyl and aryl αβ-unsaturated carboxylate ions; 2-butenoate was the best substrate tested.

Links to other databases

References

1. Tischer, W., Bader, J. and Simon, H.
   Purification and some properties of a hitherto-unknown enzyme reducing the carbon-carbon double bond of α,β-unsaturated carboxylate anions.
   Eur. J. Biochem. 97: 103-112 (1979). [PMID: 477658]

[EC 1.3.1.31 created 1982]