EC - Prephenate dehydrogenase

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IntEnz Enzyme Nomenclature


Accepted name:
prephenate dehydrogenase
Other names:
hydroxyphenylpyruvate synthase
chorismate mutase—prephenate dehydrogenase
Systematic name:
prephenate:NAD+ oxidoreductase (decarboxylating)



This enzyme in the enteric bacteria also possesses chorismate mutase activity (EC chorismate mutase) and converts chorismate into prephenate.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC51176
Structural data: CSA , EC2PDB
Gene Ontology: GO:0008977
CAS Registry Number: 9044-92-2
UniProtKB/Swiss-Prot: (23) [show] [UniProt]


  1. Koch, G.L.E., Shaw, D.C. and Gibson, F.
    Tyrosine biosynthesis in Aerobacter aerogenes. Purification and properties of chorismate mutase-prephenate dehydrogenase.
    Biochim. Biophys. Acta 212 : 375-386 (1970). [PMID: 5456988]

[EC created 1972]