EC - Enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)

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IntEnz Enzyme Nomenclature


Accepted name:
enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
Other names:
NADPH 2-enoyl Co A reductase
acyl-ACP dehydrogenase [ambiguous]
enoyl acyl-carrier-protein reductase [ambiguous]
enoyl-ACP reductase [ambiguous]
enoyl-[acyl carrier protein] (reduced nicotinamide adenine dinucleotide phosphate) reductase
enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific)
acyl-[acyl-carrier-protein]:NADP+ oxidoreductase (B-specific)
acyl-[acyl-carrier protein]:NADP+ oxidoreductase (B-specific)
Systematic name:
acyl-[acyl-carrier-protein]:NADP+ oxidoreductase (Si-specific)



One of the activities of EC, fatty-acyl-CoA synthase system, an enzyme found in yeasts (Ascomycota and the Basidiomycota). Catalyses the reduction of enoyl-acyl-[acyl-carrier protein] derivatives of carbon chain length from 4 to 16. The yeast enzyme is Si-specific with respect to NADP+. cf. EC, enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific) and EC, enoyl-[acyl-carrier-protein] reductase (NADPH), which describes enzymes whose stereo-specificity towards NADPH is not known. See also EC, enoyl-[acyl-carrier-protein] reductase (NADH).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004319
CAS Registry Number: 37251-09-5


  1. Seyama, T., Kasama, T., Yamakawa, T., Kawaguchi, A., Saito, K. and Okuda, S.
    Origin of hydrogen atoms in the fatty acids synthesized with yeast fatty acid synthetase.
    J. Biochem. (Tokyo) 82 : 1325-1329 (1977). [PMID: 338601]

[EC created 1972, modified 1986, modified 2013, modified 2014]