IntEnz

EC 1.21.3.4 - Sulochrin oxidase [(+)-bisdechlorogeodin-forming]

IntEnz Enzyme Nomenclature
EC 1.21.3.4

Names

Reaction

• 24092 [IUBMB]
  2

  H⁺

  H(+)

  Name origin: UniProt - CHECKED (C)

  CHEBI:15378

  Formula: H
  Charge: 1

  ChEBI compound status: CHECKED (C)

  

  +

  O₂

  O2

  Name origin: UniProt - CHECKED (C)

  CHEBI:15379

  Formula: O2
  Charge: 0

  ChEBI compound status: CHECKED (C)

  

  +

  2

  sulochrin

  sulochrin

  Name origin: UniProt - CHECKED (C)

  CHEBI:77639

  Formula: C17H15O7
  Charge: -1

  ChEBI compound status: CHECKED (C)

  

  =

  2

  (2S)-bisdechlorogeodin

  (2S)-bisdechlorogeodin

  Name origin: UniProt - CHECKED (C)

  CHEBI:15390

  Formula: C17H14O7
  Charge: 0

  ChEBI compound status: CHECKED (C)

  

  +

  2

  H₂O

  H2O

  Name origin: UniProt - CHECKED (C)

  CHEBI:15377

  Formula: H2O
  Charge: 0

  ChEBI compound status: CHECKED (C)

  

Comments:

Also acts on several diphenols and phenylenediamines, but has low affinity for these substrates. Involved in the biosynthesis of mould metabolites related to the antibiotic griseofulvin.

Links to other databases

References

1. Nordlöv, H. and Gatenbeck, S.
   Enzymatic synthesis of (+)- and (−)-bisdechlorogeodin with sulochrin oxidase from Penicillium frequentans and Oospora sulphurea ochracea.
   Arch. Microbiol. 131 : 208-211 (1982). [PMID: 7049104]

[EC 1.21.3.4 created 1986 as EC 1.10.3.7, transferred 2002 to EC 1.21.3.4]