EC 1.21.3.2 - Columbamine oxidase

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IntEnz Enzyme Nomenclature
EC 1.21.3.2

Names

Accepted name:
columbamine oxidase
Other name:
berberine synthase
Systematic name:
columbamine:oxygen oxidoreductase (cyclizing)

Reaction

Cofactor

Comments:

An iron protein. Oxidation of the O-methoxyphenol structure forms the methylenedioxy group of berberine.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0050455
CAS Registry Number: 95329-18-3

References

  1. Rueffer, M. and Zenk, M.H.
    Berberine synthesis, the methylenedioxy group forming enzyme in berberine synthesis.
    Tetrahedron Lett. 26: 201-202 (1985).

[EC 1.21.3.2 created 1989 as EC 1.1.3.26, transferred 2002 to EC 1.21.3.2]