IntEnz

EC 1.21.3.2 - Columbamine oxidase

IntEnz Enzyme Nomenclature
EC 1.21.3.2

Names

Reaction

• 23564 [IUBMB]
  2

  columbamine

  columbamine

  Name origin: UniProt - CHECKED (C)

  CHEBI:15920

  Formula: C20H20NO4
  Charge: 1

  ChEBI compound status: CHECKED (C)

  

  +

  O₂

  O2

  Name origin: UniProt - CHECKED (C)

  CHEBI:15379

  Formula: O2
  Charge: 0

  ChEBI compound status: CHECKED (C)

  

  =

  2

  berberine

  berberine

  Name origin: UniProt - CHECKED (C)

  CHEBI:16118

  Formula: C20H18NO4
  Charge: 1

  ChEBI compound status: CHECKED (C)

  

  +

  2

  H₂O

  H2O

  Name origin: UniProt - CHECKED (C)

  CHEBI:15377

  Formula: H2O
  Charge: 0

  ChEBI compound status: CHECKED (C)

  

Cofactor

• Fe cation

Comments:

An iron protein. Oxidation of the O-methoxyphenol structure forms the methylenedioxy group of berberine.

Links to other databases

References

1. Rueffer, M. and Zenk, M.H.
   Berberine synthesis, the methylenedioxy group forming enzyme in berberine synthesis.
   Tetrahedron Lett. 26: 201-202 (1985).

[EC 1.21.3.2 created 1989 as EC 1.1.3.26, transferred 2002 to EC 1.21.3.2]