EC 1.20.4.3 - Mycoredoxin

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IntEnz Enzyme Nomenclature
EC 1.20.4.3

Names

Accepted name:
mycoredoxin
Other names:
Mrx1
MrxI
Systematic name:
arseno-mycothiol:mycoredoxin oxidoreductase

Reaction

Comments:

Reduction of arsenate is part of a defense mechanism of the cell against toxic arsenate. The substrate arseno-mycothiol is formed by EC 2.8.4.2 (arsenate:mycothiol transferase). A second mycothiol recycles mycoredoxin and forms mycothione.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Ordonez, E., Van Belle, K., Roos, G., De Galan, S., Letek, M., Gil, J. A., Wyns, L., Mateos, L. M., Messens, J.
    Arsenate reductase, mycothiol, and mycoredoxin concert thiol/disulfide exchange.
    J. Biol. Chem. 284 : 15107-15116 (2009). [PMID: 19286650]

[EC 1.20.4.3 created 2010]