EC - Aldehyde dehydrogenase (quinone)

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IntEnz Enzyme Nomenclature


Accepted name:
aldehyde dehydrogenase (quinone)
Other name:
aldehyde dehydrogenase (acceptor)
Systematic name:
aldehyde:quinone oxidoreductase




Wide specificity; acts on straight-chain aldehydes up to C10, aromatic aldehydes, glyoxylate and glyceraldehyde. The enzymes contains a PQQ cofactor and multiple hemes that deliver the electrons to the membrane quinone pool.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047113
CAS Registry Number: 75536-77-5


  1. Ameyama, M. and Adachi, O.
    Aldehyde dehydrogenase from acetic acid bacteria, membrane-bound.
    Methods Enzymol. 89 : 491-497 (1982).
  2. Ameyama, M., Osada, K., Shinagawa, E., Matsushita, K. and Adachi, O.
    Purification and characterization of aldehyde dehydrogenase of Acetobacter aceti.
    Agric. Biol. Chem. 45 : 1189-1890 (1981).
  3. Patel, R.N., Hou, C.T., Derelanko,P. and Felix, A.
    Purification and properties of a heme-containing aldehyde dehydrogenase from Methylosinus trichosporium.
    Arch. Biochem. Biophys. 203 : 654-662 (1980). [PMID: 6779711]
  4. Gomez-Manzo, S., Chavez-Pacheco, J. L., Contreras-Zentella, M., Sosa-Torres, M. E., Arreguin-Espinosa, R., Perez de la Mora, M., Membrillo-Hernandez, J., Escamilla, J. E.
    Molecular and catalytic properties of the aldehyde dehydrogenase of Gluconacetobacter diazotrophicus, a quinoheme protein containing pyrroloquinoline quinone, cytochrome b, and cytochrome c.
    J. Bacteriol. 192 : 5718-5724 (2010). [PMID: 20802042]

[EC created 1983 as EC, modified 1989, transferred 2015 to EC]