EC - 4-hydroxybenzaldehyde dehydrogenase (NADP+)

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature


Accepted name:
4-hydroxybenzaldehyde dehydrogenase (NADP+)
Other names:
p-hydroxybenzaldehyde dehydrogenase [ambiguous]
pchA (gene name)
Systematic name:
4-hydroxybenzaldehyde:NADP+ oxidoreductase



Involved in the aerobic pathway for degradation of toluene, 4-methylphenol, and 2,4-xylenol by several Pseudomonas strains. The enzyme is also active with 4-hydroxy-3-methylbenzaldehyde. cf. EC, 4-hydroxybenzaldehyde dehydrogenase (NAD+).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB


  1. Whited, G. M., Gibson, D. T.
    Separation and partial characterization of the enzymes of the toluene-4-monooxygenase catabolic pathway in Pseudomonas mendocina KR1.
    J. Bacteriol. 173 : 3017-3020 (1991). [PMID: 2019564]
  2. Chen, Y. F., Chao, H., Zhou, N. Y.
    The catabolism of 2,4-xylenol and p-cresol share the enzymes for the oxidation of para-methyl group in Pseudomonas putida NCIMB 9866.
    Appl. Microbiol. Biotechnol. 98 : 1349-1356 (2014). [PMID: 23736872]

[EC created 2015]