EC - Farnesal dehydrogenase

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IntEnz Enzyme Nomenclature


Accepted name:
farnesal dehydrogenase
Other name:
Systematic name:
farnesal:NAD+ oxidoreductase



Invoved in juvenile hormone production in insects. The enzyme was described from the corpora allata of Drosophila melanogaster (fruit fly), Manduca sexta (tobacco hornworm) and Aedes aegypti (dengue mosquito).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB


  1. Madhavan, K., Conscience-Egli, M., Sieber, F., Ursprung, H.
    Farnesol metabolism in Drosophila melanogaster: ontogeny and tissue distribution of octanol dehydrogenase and aldehyde oxidase.
    J. Insect Physiol. 19 : 235-241 (1973). [PMID: 4631837]
  2. Baker, F. C., Mauchamp, B., Tsai, L. W., Schooley, D. A.
    Farnesol and farnesal dehydrogenase(s) in corpora allata of the tobacco hornworm moth, Manduca sexta.
    J. Lipid Res. 24 : 1586-1594 (1983). [PMID: 6366103]
  3. Rivera-Perez, C., Nouzova, M., Clifton, M. E., Garcia, E. M., LeBlanc, E., Noriega, F. G.
    Aldehyde dehydrogenase 3 converts farnesal into farnesoic acid in the corpora allata of mosquitoes.
    Insect Biochem. Mol. Biol. 43 : 675-682 (2013). [PMID: 23639754]

[EC created 2015]