EC 1.2.1.94 - Farnesal dehydrogenase

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IntEnz Enzyme Nomenclature
EC 1.2.1.94

Names

Accepted name:
farnesal dehydrogenase
Other name:
AaALDH3
Systematic name:
farnesal:NAD+ oxidoreductase

Reaction

Comments:

Invoved in juvenile hormone production in insects. The enzyme was described from the corpora allata of Drosophila melanogaster (fruit fly), Manduca sexta (tobacco hornworm) and Aedes aegypti (dengue mosquito).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Madhavan, K., Conscience-Egli, M., Sieber, F., Ursprung, H.
    Farnesol metabolism in Drosophila melanogaster: ontogeny and tissue distribution of octanol dehydrogenase and aldehyde oxidase.
    J. Insect Physiol. 19: 235-241 (1973). [PMID: 4631837]
  2. Baker, F. C., Mauchamp, B., Tsai, L. W., Schooley, D. A.
    Farnesol and farnesal dehydrogenase(s) in corpora allata of the tobacco hornworm moth, Manduca sexta.
    J. Lipid Res. 24: 1586-1594 (1983). [PMID: 6366103]
  3. Rivera-Perez, C., Nouzova, M., Clifton, M. E., Garcia, E. M., LeBlanc, E., Noriega, F. G.
    Aldehyde dehydrogenase 3 converts farnesal into farnesoic acid in the corpora allata of mosquitoes.
    Insect Biochem. Mol. Biol. 43: 675-682 (2013). [PMID: 23639754]

[EC 1.2.1.94 created 2015]