EC 1.2.1.89 - D-glyceraldehyde dehydrogenase (NADP+)

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IntEnz Enzyme Nomenclature
EC 1.2.1.89

Names

Accepted name:
D-glyceraldehyde dehydrogenase (NADP+)
Other names:
glyceraldehyde dehydrogenase
GADH
Systematic name:
D-glyceraldehyde:NADP+ oxidoreductase

Reaction

Comments:

The enzyme from the archaea Thermoplasma acidophilum and Picrophilus torridus is involved in the non-phosphorylative Entner-Doudoroff pathway. cf. EC 1.2.99.8, glyceraldehyde dehydrogenase (FAD-containing).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0043796
UniProtKB/Swiss-Prot:

References

  1. Jung, J. H., Lee, S. B.
    Identification and characterization of Thermoplasma acidophilum glyceraldehyde dehydrogenase: a new class of NADP+-specific aldehyde dehydrogenase.
    Biochem. J. 397: 131-138 (2006). [PMID: 16566751]
  2. Reher, M., Schonheit, P.
    Glyceraldehyde dehydrogenases from the thermoacidophilic euryarchaeota Picrophilus torridus and Thermoplasma acidophilum, key enzymes of the non-phosphorylative Entner-Doudoroff pathway, constitute a novel enzyme family within the aldehyde dehydrogenase superfamily.
    FEBS Lett. 580: 1198-1204 (2006). [PMID: 16458304]

[EC 1.2.1.89 created 2014]