EC - 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase (NADP+)

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IntEnz Enzyme Nomenclature


Accepted name:
3,4-dehydroadipyl-CoA semialdehyde dehydrogenase (NADP+)
Other names:
3,4-dehydroadipyl-CoA semialdehyde dehydrogenase
Systematic name:
3,4-dehydroadipyl-CoA semialdehyde:NADP+ oxidoreductase



This enzyme catalyses a step in the aerobic benzoyl-coenzyme A catabolic pathway in Azoarcus evansii and Burkholderia xenovorans. Formerly EC 1.2.1.n1.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00068
Structural data: CSA , EC2PDB


  1. Gescher, J., Ismail, W., Olgeschlager, E., Eisenreich, W., Worth, J., Fuchs, G.
    Aerobic benzoyl-coenzyme A (CoA) catabolic pathway in Azoarcus evansii: conversion of ring cleavage product by 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase.
    J. Bacteriol. 188 : 2919-2927 (2006). [PMID: 16585753]
  2. Bains, J., Boulanger, M. J.
    Structural and biochemical characterization of a novel aldehyde dehydrogenase encoded by the benzoate oxidation pathway in Burkholderia xenovorans LB400.
    J. Mol. Biol. 379 : 597-608 (2008). [PMID: 18462753]

[EC created 2010]