EC 1 - Oxidoreductases
EC 1.2 - Acting on the aldehyde or oxo group of donors
EC 1.2.1 - With NAD+ or NADP+ as acceptor
EC 1.2.1.60 - 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 1.2.1.60
Names
Accepted name:
5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase
Other
name:
carboxymethylhydroxymuconic semialdehyde dehydrogenase
Systematic name:
5-carboxymethyl-2-hydroxymuconic-semialdehyde:NAD+ oxidoreductase
Reaction
- 5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+ = 5-carboxymethyl-2-hydroxymuconate + NADH + H+
Comments:
Involved in the tyrosine degradation pathway in Arthrobacter sp.
Links to other databases
Enzymes and pathways:
NC-IUBMB
,
BRENDA
,
ExplorEnz
,
ENZYME@ExPASy
,
KEGG
,
MetaCyc
,
UM-BBD
,
UniPathway
Gene Ontology:
GO:0018480
References
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The catabolism of L-tyrosine by an Arthrobacter sp.Can. J. Microbiol. 23 : 1128-1139 (1977). [PMID: 20216]
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Carboxymethylhydroxymuconic semialdehyde dehydrogenase in the 4-hydroxyphenylacetate catabolic pathway of Escherichia coli.Biochim. Biophys. Acta 719 : 165-167 (1982). [PMID: 6756482]
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Catabolism of 3- and 4-hydroxyphenylacetate by the3,4-dihydroxyphenylacetate pathway in Escherichia coli.J. Bacteriol. 143 : 302-306 (1980). [PMID: 6995433]
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Identification and purification of distinct isomerase and decarboxylase enzymes involved in the 4-hydroxyphenylacetate pathway of Escherichia coli.Eur. J. Biochem. 117 : 581-584 (1981).
[EC 1.2.1.60 created 2000]