EC - Long-chain-fatty-acyl-CoA reductase

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IntEnz Enzyme Nomenclature


Accepted name:
long-chain-fatty-acyl-CoA reductase
Other names:
acyl coenzyme A reductase
acyl-CoA reductase
Systematic name:
long-chain-aldehyde:NADP+ oxidoreductase (acyl-CoA-forming)



Together with EC long-chain-fatty-acid-luciferin-component ligase, forms a fatty acid reductase system that produces the substrate of EC alkanal monooxygenase (FMN-linked), thus being part of the bacterial luciferase system.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0050062
CAS Registry Number: 50936-56-6


  1. Riendeau, D., Rodrigues, A. and Meighen, E.
    Resolution of the fatty acid reductase from Photobacterium phosphoreum into acyl protein synthetase and acyl-CoA reductase activities. Evidence for an enzyme complex.
    J. Biol. Chem. 257 : 6908-6915 (1982). [PMID: 7085612]
  2. Wall, L. and Meighen, E.A.
    Subunit structure of the fatty-acid reductase complex from Photobacterium phosphoreum.
    Biochemistry 25 : 4315-4321 (1986).

[EC created 1986]