IntEnz - EC 1.2.1.20

EC 1 - Oxidoreductases

EC 1.2 - Acting on the aldehyde or oxo group of donors

EC 1.2.1 - With NAD⁺ or NADP⁺ as acceptor

EC 1.2.1.20 - Glutarate-semialdehyde dehydrogenase

IntEnz view ENZYME view

IntEnz Enzyme Nomenclature
EC 1.2.1.20

Names

Accepted name:

glutarate-semialdehyde dehydrogenase

Other name:

glutarate semialdehyde dehydrogenase

Systematic name:

glutarate-semialdehyde:NAD⁺ oxidoreductase

Reaction

12064 [IUBMB]

5-oxopentanoate

5-oxopentanoate

Name origin: UniProt - CHECKED (C)

CHEBI:16120

Formula: C5H7O3
Charge: -1

ChEBI compound status: CHECKED (C)

+

H₂O

H2O

Name origin: UniProt - CHECKED (C)

CHEBI:15377

Formula: H2O
Charge: 0

ChEBI compound status: CHECKED (C)

+

NAD⁺

NAD(+)

Name origin: UniProt - CHECKED (C)

CHEBI:57540

Formula: C21H26N7O14P2
Charge: -1

ChEBI compound status: CHECKED (C)

=

glutarate

glutarate

Name origin: UniProt - CHECKED (C)

CHEBI:30921

Formula: C5H6O4
Charge: -2

ChEBI compound status: CHECKED (C)

+
2

H⁺

H(+)

Name origin: UniProt - CHECKED (C)

CHEBI:15378

Formula: H
Charge: 1

ChEBI compound status: CHECKED (C)

+

NADH

NADH

Name origin: UniProt - CHECKED (C)

CHEBI:57945

Formula: C21H27N7O14P2
Charge: -2

ChEBI compound status: CHECKED (C)

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway

Structural data: CSA , EC2PDB

Gene Ontology: GO:0047949

CAS Registry Number: 9028-99-3

References

Ichihara, A. and Ichihara, E.A.

Metabolism of L-lysine by bacterial enzymes. V. Glutaric semialdehyde dehydrogenase.

J. Biochem. (Tokyo) 49: 154-157 (1961).

[EC 1.2.1.20 created 1965]