EC - Malonate-semialdehyde dehydrogenase (acetylating)

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IntEnz Enzyme Nomenclature


Accepted name:
malonate-semialdehyde dehydrogenase (acetylating)
Other name:
malonic semialdehyde oxidative decarboxylase
Systematic name:
3-oxopropanoate:NAD(P)+ oxidoreductase (decarboxylating, CoA-acetylating)


Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0018478
CAS Registry Number: 9028-97-1
UniProtKB/Swiss-Prot: (12) [show] [UniProt]


  1. Hayaishi, O., Nishizuka, Y., Tatibana, M., Takeshita, M. and Kuno, S.
    Enzymatic studies on the metabolism of β-alanine.
    J. Biol. Chem. 236 : 781-790 (1961).
  2. Jakoby, W.B.
    Aldehyde dehydrogenase.
    In: Boyer, P.D., Lardy, H. and Myrbäck, K. (Eds.) The Enzymes , 2nd ed. vol. 7 , Academic Press , New York , 1963 , 203-221
  3. Yamada, E.W. and Jakoby, W.B.
    Aldehyde oxidation. V. Direct conversion of malonic semialdehyde to acetyl-coenzyme A.
    J. Biol. Chem. 235 : 589-594 (1960).

[EC created 1965]