EC - 3-oxo-Δ1-steroid hydratase/dehydrogenase

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IntEnz Enzyme Nomenclature


Accepted name:
3-oxo-Δ1-steroid hydratase/dehydrogenase
Systematic name:
3-oxo-Δ1-steroid:acceptor 1-oxidoreductase



A molybdenum enzyme. The enzyme, characterized from the bacterium Steroidobacter denitrificans, is involved in the anaetrobic degradation of steroids. It is specific to 3-oxo-Δ1-steroids such as androsta-1-ene-3,17-dione and Δ1-dihydrotestosterone and does not act on 3-oxo-Δ4-steroids.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB


  1. Yang, F. C., Chen, Y. L., Tang, S. L., Yu, C. P., Wang, P. H., Ismail, W., Wang, C. H., Ding, J. Y., Yang, C. Y., Yang, C. Y., Chiang, Y. R.
    Integrated multi-omics analyses reveal the biochemical mechanisms and phylogenetic relevance of anaerobic androgen biodegradation in the environment.
    ISME J 10 : 1967-1983 (2016). [PMID: 26872041]

[EC created 2020]