EC 1.17.99.11 - 3-oxo-Δ1-steroid hydratase/dehydrogenase

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IntEnz Enzyme Nomenclature
EC 1.17.99.11

Names

Accepted name:
3-oxo-Δ1-steroid hydratase/dehydrogenase
Systematic name:
3-oxo-Δ1-steroid:acceptor 1-oxidoreductase

Reactions

Comments:

A molybdenum enzyme. The enzyme, characterized from the bacterium Steroidobacter denitrificans, is involved in the anaetrobic degradation of steroids. It is specific to 3-oxo-Δ1-steroids such as androsta-1-ene-3,17-dione and Δ1-dihydrotestosterone and does not act on 3-oxo-Δ4-steroids.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB

References

  1. Yang, F. C., Chen, Y. L., Tang, S. L., Yu, C. P., Wang, P. H., Ismail, W., Wang, C. H., Ding, J. Y., Yang, C. Y., Yang, C. Y., Chiang, Y. R.
    Integrated multi-omics analyses reveal the biochemical mechanisms and phylogenetic relevance of anaerobic androgen biodegradation in the environment.
    ISME J 10 : 1967-1983 (2016). [PMID: 26872041]

[EC 1.17.99.11 created 2020]