EC 1.17.98.3 - Formate dehydrogenase (coenzyme F420)

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IntEnz Enzyme Nomenclature
EC 1.17.98.3

Names

Accepted name:
formate dehydrogenase (coenzyme F420)
Other names:
coenzyme F420 reducing formate dehydrogenase
coenzyme F420-dependent formate dehydrogenase
Systematic name:
formate:coenzyme-F420 oxidoreductase

Reaction

Cofactor

Comments:

The enzyme from methanogenic archaea is a involved in formate-dependent H2 production. It contains noncovalently bound FAD [1].

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB

References

  1. Schauer, N. L., Ferry, J. G.
    FAD requirement for the reduction of coenzyme F420 by formate dehydrogenase from Methanobacterium formicicum.
    J. Bacteriol. 155 : 467-472 (1983). [PMID: 6874636]
  2. Schauer, N. L., Ferry, J. G.
    Composition of the coenzyme F420-dependent formate dehydrogenase from Methanobacterium formicicum.
    J. Bacteriol. 165 : 405-411 (1986). [PMID: 3944055]
  3. Lupa, B., Hendrickson, E. L., Leigh, J. A., Whitman, W. B.
    Formate-dependent H2 production by the mesophilic methanogen Methanococcus maripaludis.
    Appl. Environ. Microbiol. 74 : 6584-6590 (2008). [PMID: 18791018]

[EC 1.17.98.3 created 2014 as EC 1.2.99.9, transferred 2017 to EC 1.17.98.3]