EC - Monoprenyl isoflavone epoxidase

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IntEnz Enzyme Nomenclature


Accepted name:
monoprenyl isoflavone epoxidase
Other names:
7-O-methylluteone:O2 oxidoreductase
monoprenyl isoflavone monooxygenase
Systematic name:
7-O-methylluteone,NADPH:O2 oxidoreductase




A flavoprotein (FAD) with high specificity for monoprenyl isoflavone. The product of the prenyl epoxidation reaction contains an oxygen atom derived from O2, but not from H2O. It is slowly and nonenzymically converted into the corresponding dihydrofurano derivative. The enzyme in the fungus Botrytis cinerea is induced by the substrate analogue, 6-prenylnaringenin.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0050602


  1. Tanaka, M. and Tahara, S.
    FAD-dependent epoxidase as a key enzyme in fungal metabolism of prenylated flavonoids.
    Phytochemistry 46 : 433-439 (1997).

[EC created 2000]