EC 1.14.99.29 - Deoxyhypusine monooxygenase

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IntEnz Enzyme Nomenclature
EC 1.14.99.29

Names

Accepted name:
deoxyhypusine monooxygenase
Other names:
deoxyhypusine dioxygenase
deoxyhypusine hydroxylase
DOHH
Systematic name:
deoxyhypusine,hydrogen-donor:oxygen oxidoreductase (2-hydroxylating)

Reaction

Comments:

The enzyme catalyses the final step in the formation of the amino acid hypusine in the eukaryotic initiation factor 5A.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0019135
CAS Registry Number: 101920-83-6
UniProtKB/Swiss-Prot: (40) [show] [UniProt]

References

  1. Abbruzzese, A., Park, M.H. and Folk, J.E.
    Deoxyhypusine hydroxylase from rat testis. Partial purification and characterization.
    J. Biol. Chem. 261: 3085-3089 (1986). [PMID: 3949761]

[EC 1.14.99.29 created 1989]