EC 1.14.19.8 - Pentalenolactone synthase

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IntEnz Enzyme Nomenclature
EC 1.14.19.8

Names

Accepted name:
pentalenolactone synthase
Other names:
penM (gene name)
pntM (gene name)
Systematic name:
pentalenolactone-reduced-ferredoxin:oxygen oxidoreductase (pentalenolactone forming)

Reaction

Cofactor

Comments:

A heme-thiolate protein (P450). Isolated from the bacteria Streptomyces exfoliatus and Streptomyces arenae.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Zhu, D., Seo, M. J., Ikeda, H., Cane, D. E.
    Genome mining in streptomyces. Discovery of an unprecedented P450-catalyzed oxidative rearrangement that is the final step in the biosynthesis of pentalenolactone.
    J. Am. Chem. Soc. 133 : 2128-2131 (2011). [PMID: 21284395]

[EC 1.14.19.8 created 2012 as EC 1.3.7.10, transferred to EC 1.14.19.8 2013]