EC 1.14.19.51 - (S)-corytuberine synthase

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IntEnz Enzyme Nomenclature
EC 1.14.19.51

Names

Accepted name:
(S)-corytuberine synthase
Other name:
CYP80G2
Systematic name:
(S)-reticuline,NADPH:oxygen oxidoreductase (C-C phenol-coupling; (S)-corytuberine-forming)

Reaction

Comments:

A cytochrome P450 (heme-thiolate) protein. The enzyme is involved in the biosynthesis of the quaternary benzylisoquinoline alkaloid magnoflorine in the plant Coptis japonica. It is specific for (S)-reticuline.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0102963
UniProtKB/Swiss-Prot:

References

  1. Ikezawa, N., Iwasa, K., Sato, F.
    Molecular cloning and characterization of CYP80G2, a cytochrome P450 that catalyzes an intramolecular C-C phenol coupling of (S)-reticuline in magnoflorine biosynthesis, from cultured Coptis japonica cells.
    J. Biol. Chem. 283 : 8810-8821 (2008). [PMID: 18230623]

[EC 1.14.19.51 created 2017]