EC 1.14.19.42 - Palmitoyl-[glycerolipid] 7-desaturase

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature
EC 1.14.19.42

Names

Accepted name:
palmitoyl-[glycerolipid] 7-desaturase
Other name:
FAD5
Systematic name:
1-acyl-2-palmitoyl-[glycerolipid],ferredoxin:oxygen oxidoreductase (7,8-cis-dehydrogenating)

Reaction

Comments:

The enzyme introduces a cis double bond at carbon 7 of a palmitoyl group attached to the sn-2 position of glycerolipids. The enzyme from the plant Arabidopsis thaliana is specific for palmitate in monogalactosyldiacylglycerol.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0102657 , GO:0102843
UniProtKB/Swiss-Prot:

References

  1. Kunst, L., Browse, J., Somerville, C.R.
    A mutant of Arabidopsis deficient in desaturation of palmitic acid in leaf lipids.
    Plant Physiol. 90 : 943-947 (1989).
  2. Heilmann, I., Mekhedov, S., King, B., Browse, J., Shanklin, J.
    Identification of the Arabidopsis palmitoyl-monogalactosyldiacylglycerol delta7-desaturase gene FAD5, and effects of plastidial retargeting of Arabidopsis desaturases on the fad5 mutant phenotype.
    Plant Physiol. 136 : 4237-4245 (2004). [PMID: 15579662]

[EC 1.14.19.42 created 2015]