EC 1.14.19.33 - Δ12 acyl-lipid conjugase (11E,13E-forming)

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature
EC 1.14.19.33

Names

Accepted name:
Δ12 acyl-lipid conjugase (11E,13E-forming)
Other names:
fatty acid Δ12-conjugase [ambiguous]
FADX (gene name)
Systematic name:
Δ12 acyl-lipid,ferrocytochrome-b5:oxygen 11,14 allylic oxidase (11E,13E-forming)

Reactions

Comments:

The enzyme, characterized from the plants Impatiens balsamina, Momordica charantia (bitter gourd) and Vernicia fordii (tung tree), converts a single cis double bond at carbon 12 to two conjugated trans bonds at positions 11 and 13. The enzyme from Vernicia fordii can also act as a 12(E) desaturase when acting on the monounsaturated fatty acids oleate and palmitoleate. cf. EC 1.14.19.16, linoleoyl-lipid Δ12 conjugase (11E,13Z-forming).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Cahoon, E. B., Carlson, T. J., Ripp, K. G., Schweiger, B. J., Cook, G. A., Hall, S. E., Kinney, A. J.
    Biosynthetic origin of conjugated double bonds: production of fatty acid components of high-value drying oils in transgenic soybean embryos.
    Proc. Natl. Acad. Sci. U.S.A. 96 : 12935-12940 (1999). [PMID: 10536026]
  2. Dyer, J. M., Chapital, D. C., Kuan, J. C., Mullen, R. T., Turner, C., McKeon, T. A., Pepperman, A. B.
    Molecular analysis of a bifunctional fatty acid conjugase/desaturase from tung. Implications for the evolution of plant fatty acid diversity.
    Plant Physiol. 130 : 2027-2038 (2002). [PMID: 12481086]

[EC 1.14.19.33 created 2015]