EC - Icosanoyl-CoA 5-desaturase

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IntEnz Enzyme Nomenclature


Accepted name:
icosanoyl-CoA 5-desaturase
Other name:
acyl-CoA Δ5-desaturase [ambiguous]
Systematic name:
icosanoyl-CoA,ferrocytochrome b5:oxygen oxidoreductase (5,6 cis-dehydrogenating)



The enzyme, characterized from the plant Limnanthes douglasii (meadowfoam), is involved in the biosynthesis of (5Z)-icos-5-enoate, an unusual monounsaturated fatty acid that makes up to 60% of the total fatty acids in Limnanthes sp. seed oil. The enzyme only acts on saturated fatty acids.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB


  1. Cahoon, E. B., Marillia, E. F., Stecca, K. L., Hall, S. E., Taylor, D. C., Kinney, A. J.
    Production of fatty acid components of meadowfoam oil in somatic soybean embryos.
    Plant Physiol. 124: 243-251 (2000). [PMID: 10982439]

[EC created 2015]