EC 1.14.15.32 - Pentalenene oxygenase

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IntEnz Enzyme Nomenclature
EC 1.14.15.32

Names

Accepted name:
pentalenene oxygenase
Other name:
PtlI
Systematic name:
pentalenene,reduced ferredoxin:oxygen 13-oxidoreductase

Reaction

Cofactor

Comments:

A cytochrome P450 (heme-thiolate) protein found in the bacterium Streptomyces avermitilis. The enzyme is involved in the biosynthesis of pentalenolactone and related antibiotics. Formerly EC 1.14.13.133.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Quaderer, R., Omura, S., Ikeda, H., Cane, D. E.
    Pentalenolactone biosynthesis. Molecular cloning and assignment of biochemical function to PtlI, a cytochrome P450 of Streptomyces avermitilis.
    J. Am. Chem. Soc. 128 : 13036-13037 (2006). [PMID: 17017767]

[EC 1.14.15.32 created 2011 as EC 1.14.13.133, transferred 2018 to EC 1.14.15.32]