EC - Alkane 1-monooxygenase

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IntEnz Enzyme Nomenclature


Accepted name:
alkane 1-monooxygenase
Other names:
alkane 1-hydroxylase
alkane hydroxylase
alkane monooxygenase
fatty acid ω-hydroxylase
Systematic name:
alkane,reduced-rubredoxin:oxygen 1-oxidoreductase



Some enzymes in this group are heme-thiolate proteins (P-450). Also hydroxylates fatty acids in the ω-position.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UM-BBD , UniPathway
Protein domains and families: PROSITE:PDOC00081
Structural data: CSA , EC2PDB
Gene Ontology: GO:0018685 , GO:0052869
CAS Registry Number: 9059-16-9


  1. Cardini, G. and Jurtshuk, P.
    The enzymatic hydroxylation of n-octane by Corynebacterium sp. strain 7E1C.
    J. Biol. Chem. 245 : 2789-2796 (1970). [PMID: 4317878]
  2. McKenna, E.J. and Coon, M.J.
    Enzymatic ω-oxidation. IV. Purification and properties of the ω-hydroxylase of Pseudomonas oleovorans.
    J. Biol. Chem. 245 : 3882-3889 (1970). [PMID: 4395379]
  3. Peterson, J.A., Kusunose, M., Kusunose, E. and Coon, M.J.
    Enzymatic ω-oxidation. II. Function of rubredoxin as the electron carrier in ω-hydroxylation.
    J. Biol. Chem. 242 : 4334-4340 (1967). [PMID: 4294330]

[EC created 1972]