EC 1.14.14.8 - Anthranilate 3-monooxygenase (FAD)

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IntEnz Enzyme Nomenclature
EC 1.14.14.8

Names

Accepted name:
anthranilate 3-monooxygenase (FAD)
Other names:
anthranilate 3-hydroxylase
anthranilate hydroxylase
Systematic name:
anthranilate,FAD:oxygen oxidoreductase (3-hydroxylating)

Reaction

Comments:

This enzyme, isolated from the bacterium Geobacillus thermodenitrificans, participates in the pathway of tryptophan degradation. The enzyme is part of a system that also includes a bifunctional riboflavin kinase/FMN adenylyltransferase and an FAD reductase, which ensures ample supply of FAD to the monooxygenase.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Liu, X., Dong, Y., Li, X., Ren, Y., Li, Y., Wang, W., Wang, L., Feng, L.
    Characterization of the anthranilate degradation pathway in Geobacillus thermodenitrificans NG80-2.
    Microbiology 156: 589-595 (2010). [PMID: 19942660]

[EC 1.14.14.8 created 2010]