EC - ent-isokaurene C2/C3-hydroxylase

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IntEnz Enzyme Nomenclature


Accepted name:
ent-isokaurene C2/C3-hydroxylase
Other names:
ent-isokaurene C2-hydroxylase
Systematic name:
ent-isokaurene,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (ent-isokaurene-2β,3β-diol forming)



This cytochrome P450 (heme thiolate) enzyme has been characterized from the plant Oryza sativa (rice). It may be involved in production of oryzadione. Formerly EC

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0036201


  1. Wu, Y., Hillwig, M. L., Wang, Q., Peters, R. J.
    Parsing a multifunctional biosynthetic gene cluster from rice: Biochemical characterization of CYP71Z6 and 7.
    FEBS Lett. 585 : 3446-3451 (2011). [PMID: 21985968]
  2. Kitaoka, N., Wu, Y., Xu, M., Peters, R. J.
    Optimization of recombinant expression enables discovery of novel cytochrome P450 activity in rice diterpenoid biosynthesis.
    Appl. Microbiol. Biotechnol. 99 : 7549-7558 (2015). [PMID: 25758958]

[EC created 2012 as EC, transferred 2018 to EC]