EC 1 - Oxidoreductases
EC 1.14 - Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2
EC 1.14.14 - With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
EC 1.14.14.5 - Alkanesulfonate monooxygenase
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 1.14.14.5
Names
Accepted name:
alkanesulfonate monooxygenase
Other
names:
SsuD
sulfate starvation-induced protein 6
FMNH2-dependent aliphatic sulfonate monooxygenase
sulfate starvation-induced protein 6
FMNH2-dependent aliphatic sulfonate monooxygenase
Systematic name:
alkanesulfonate, reduced-FMN:oxygen oxidoreductase
Reaction
- an alkanesulfonate (R-CH2-SO3H) + FMNH2 + O2 = an aldehyde (R-CHO) + FMN + sulfite + H2O
Comments:
The enzyme from E. coli catalyses the desulfonation of a wide range of aliphatic sulfonates (unsubstituted C1- to C14-sulfonates as well as substituted C2-sulfonates). Does not desulfonate taurine (2-aminoethanesulfonate) or aromatic sulfonates. Does not use FMN as a bound cofactor. Instead, it uses reduced FMN (i.e., FMNH2) as a substrate. FMNH2 is provided by SsuE, the associated FMN reductase (EC 1.5.1.38).
Links to other databases
Gene Ontology:
GO:0008726
CAS Registry Number:
256383-67-2
References
-
Characterization of a two-component alkanesulfonate monooxygenase from Escherichia coli.J. Biol. Chem. 274 : 26639-26646 (1999). [PMID: 10480865]
[EC 1.14.14.5 created 2002]