EC - Alkanesulfonate monooxygenase

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IntEnz Enzyme Nomenclature


Accepted name:
alkanesulfonate monooxygenase
Other names:
sulfate starvation-induced protein 6
FMNH2-dependent aliphatic sulfonate monooxygenase
Systematic name:
alkanesulfonate, reduced-FMN:oxygen oxidoreductase



The enzyme from E. coli catalyses the desulfonation of a wide range of aliphatic sulfonates (unsubstituted C1- to C14-sulfonates as well as substituted C2-sulfonates). Does not desulfonate taurine (2-aminoethanesulfonate) or aromatic sulfonates. Does not use FMN as a bound cofactor. Instead, it uses reduced FMN (i.e., FMNH2) as a substrate. FMNH2 is provided by SsuE, the associated FMN reductase (EC

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0008726
CAS Registry Number: 256383-67-2
UniProtKB/Swiss-Prot: (82) [show] [UniProt]


  1. Eichhorn, E., van der Ploeg, J.R. and Leisinger, T.
    Characterization of a two-component alkanesulfonate monooxygenase from Escherichia coli.
    J. Biol. Chem. 274 : 26639-26646 (1999). [PMID: 10480865]

[EC created 2002]