EC 1 - Oxidoreductases
EC 1.14 - Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2
EC 1.14.14 - With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
EC 1.14.14.34 - Methanesulfonate monooxygenase (FMNH2)
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 1.14.14.34
Names
Accepted name:
methanesulfonate monooxygenase (FMNH2)
Other
names:
msuD (gene name)
ssuD (gene name)
ssuD (gene name)
Systematic name:
methanesulfonate,FMNH2:oxygen oxidoreductase
Reaction
- methanesulfonate + FMNH2 + O2 = formaldehyde + FMN + sulfite + H2O
Comments:
The enzyme, characterized from Pseudomonas strains, allows the organisms to utilize methanesulfonate as their sulfur source. It acts in combination with a dedicated NADH-dependent FMN reductase (EC 1.5.1.42), which provides it with reduced FMN. cf. EC 1.14.13.111, methanesulfonate monooxygenase (NADH).
Links to other databases
References
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A novel reduced flavin mononucleotide-dependent methanesulfonate sulfonatase encoded by the sulfur-regulated msu operon of Pseudomonas aeruginosa.J. Bacteriol. 181 : 1464-1473 (1999). [PMID: 10049377]
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Characterization and identification of genes essential for dimethyl sulfide utilization in Pseudomonas putida strain DS1.Appl. Microbiol. Biotechnol. 62 : 83-91 (2003). [PMID: 12835925]
[EC 1.14.14.34 created 2016]