EC 1.14.14.164 - Fraxetin 5-hydroxylase

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IntEnz Enzyme Nomenclature
EC 1.14.14.164

Names

Accepted name:
fraxetin 5-hydroxylase
Other names:
CYP82C4
fraxetin 5-monooxygenase
Systematic name:
fraxetin,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (5-hydroxylating)

Reaction

Comments:

A cytochrome P450 (heme-thiolate) protein involved in biosynthesis of iron(III)-chelating coumarins in higher plants.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0106144
UniProtKB/Swiss-Prot:

References

  1. Rajniak, J., Giehl, R. F. H., Chang, E., Murgia, I., von Wiren, N., Sattely, E. S.
    Biosynthesis of redox-active metabolites in response to iron deficiency in plants.
    Nat. Chem. Biol. 14 : 442-450 (2018). [PMID: 29581584]

[EC 1.14.14.164 created 2018]