EC 1.14.14.148 - Angelicin synthase

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IntEnz Enzyme Nomenclature
EC 1.14.14.148

Names

Accepted name:
angelicin synthase
Other name:
CYP71AJ4
Systematic name:
(+)-columbianetin,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase

Reaction

Cofactor

Comments:

This cytochrome P450 (heme-thiolate) enzyme from wild parsnip is involved in the formation of angular furanocoumarins. Attacks its substrate by syn-elimination of hydrogen from C-3'. Formerly EC 1.14.13.115.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0102995
UniProtKB/Swiss-Prot:

References

  1. Larbat, R., Hehn, A., Hans, J., Schneider, S., Jugde, H., Schneider, B., Matern, U., Bourgaud, F.
    Isolation and functional characterization of CYP71AJ4 encoding for the first P450 monooxygenase of angular furanocoumarin biosynthesis.
    J. Biol. Chem. 284: 4776-4785 (2009). [PMID: 19098286]

[EC 1.14.14.148 created 2010 as EC 1.14.13.115, transferred 2018 to EC 1.14.14.148]