EC 1.14.13.64 - 4-hydroxybenzoate 1-hydroxylase

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IntEnz Enzyme Nomenclature
EC 1.14.13.64

Names

Accepted name:
4-hydroxybenzoate 1-hydroxylase
Other name:
4-hydroxybenzoate 1-monooxygenase
Systematic name:
4-hydroxybenzoate,NAD(P)H:oxygen oxidoreductase (1-hydroxylating, decarboxylating)

Reactions

Cofactor

Comments:

requires FAD. The enzyme from Candida parapsilosis is specific for 4-hydroxybenzoate derivatives and prefers NADH to NADPH as electron donor.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UM-BBD , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0018678
CAS Registry Number: 134214-78-1

References

  1. van Berkel, W.J.H., Eppink, M.H.M., Middelhoven, W.J., Vervoort, J. and Rietjens, I.M.C.M.
    Catabolism of 4-hydroxybenzoate in Candida parapsilosis proceeds through initial oxidative decarboxylation by a FAD-dependent 4-hydroxybenzoate 1-hydroxylase.
    FEMS Microbiol. Lett. 121: 207-216 (1994). [PMID: 7926672]

[EC 1.14.13.64 created 1999]