EC 1 - Oxidoreductases
EC 1.14 - Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2
EC 1.14.13 - With NADH or NADPH as one donor, and incorporation of one atom of oxygen
EC 1.14.13.27 - 4-aminobenzoate 1-monooxygenase
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 1.14.13.27
Names
Accepted name:
4-aminobenzoate 1-monooxygenase
Other
names:
4-aminobenzoate hydroxylase
4-aminobenzoate monooxygenase
4-aminobenzoate dehydrogenase
4-aminobenzoate monooxygenase
4-aminobenzoate dehydrogenase
Systematic name:
4-aminobenzoate,NAD(P)H:oxygen oxidoreductase (1-hydroxylating, decarboxylating)
Reaction
- 4-aminobenzoate + NAD(P)H + 2 H+ + O2 = 4-hydroxyaniline + NAD(P)+ + H2O + CO2
Cofactor
Comments:
A flavoprotein (FAD). Acts on anthranilate and 4-aminosalicylate but not on salicylate (cf. EC 1.14.13.1 salicylate 1-monooxygenase).
Links to other databases
Enzymes and pathways:
NC-IUBMB
,
BRENDA
,
ExplorEnz
,
ENZYME@ExPASy
,
KEGG
,
MetaCyc
,
UM-BBD
,
UniPathway
Gene Ontology:
GO:0018670
CAS Registry Number:
98668-55-4
References
-
Purification and properties of 4-aminobenzoate hydroxylase, a new monooxygenase from Agaricus bisporus.J. Biol. Chem. 261 : 13203-13209 (1986). [PMID: 3489713]
[EC 1.14.13.27 created 1989]