EC - Aliphatic glucosinolate S-oxygenase

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IntEnz Enzyme Nomenclature


Accepted name:
aliphatic glucosinolate S-oxygenase
Other names:
ω-(methylthio)alkylglucosinolate S-oxygenase
GS-OX1 (gene name)
Systematic name:
ω-(methylsulfanyl)alkyl-glucosinolate,NADPH:oxygen S-oxidoreductase



The enzyme is a member of the flavin-dependent monooxygenase (FMO) family (cf. EC The plant Arabidopsis thaliana contains five isoforms. GS-OX1 through GS-OX4 are able to catalyse the S-oxygenation independent of chain length, while GS-OX5 is specific for 8-(methylsulfanyl)octyl glucosinolate.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB


  1. Hansen, B. G., Kliebenstein, D. J., Halkier, B. A.
    Identification of a flavin-monooxygenase as the S-oxygenating enzyme in aliphatic glucosinolate biosynthesis in Arabidopsis.
    Plant J. 50 : 902-910 (2007). [PMID: 17461789]
  2. Li, J., Hansen, B. G., Ober, J. A., Kliebenstein, D. J., Halkier, B. A.
    Subclade of flavin-monooxygenases involved in aliphatic glucosinolate biosynthesis.
    Plant Physiol. 148 : 1721-1733 (2008). [PMID: 18799661]

[EC created 2017]