EC - Phenylacetyl-CoA 1,2-epoxidase

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IntEnz Enzyme Nomenclature


Accepted name:
phenylacetyl-CoA 1,2-epoxidase
Other names:
ring 1,2-phenylacetyl-CoA epoxidase
phenylacetyl-CoA monooxygenase
Systematic name:
phenylacetyl-CoA:oxygen oxidoreductase (1,2-epoxidizing)



Part of the aerobic pathway of phenylacetate catabolism in Escherichia coli and Pseudomonas putida. Formerly EC 1.14.13.n9.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0097266


  1. Teufel, R., Mascaraque, V., Ismail, W., Voss, M., Perera, J., Eisenreich, W., Haehnel, W., Fuchs, G.
    Bacterial phenylalanine and phenylacetate catabolic pathway revealed.
    Proc. Natl. Acad. Sci. U.S.A. 107: 14390-14395 (2010). [PMID: 20660314]
  2. Grishin, A. M., Ajamian, E., Zhang, L., Cygler, M.
    Crystallization and preliminary X-ray analysis of PaaAC, the main component of the hydroxylase of the Escherichia coli phenylacetyl-coenzyme A oxygenase complex.
    Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 66: 1045-1049 (2010). [PMID: 20823522]
  3. Grishin, A. M., Ajamian, E., Tao, L., Zhang, L., Menard, R., Cygler, M.
    Structural and functional studies of the Escherichia coli phenylacetyl-CoA monooxygenase complex.
    J. Biol. Chem. 286: 10735-10743 (2011). [PMID: 21247899]

[EC created 2012]