EC 1 - Oxidoreductases
EC 1.14 - Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2
EC 1.14.12 - With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor
EC 1.14.12.9 - 4-chlorophenylacetate 3,4-dioxygenase
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 1.14.12.9
Names
Accepted name:
4-chlorophenylacetate 3,4-dioxygenase
Systematic name:
4-chlorophenylacetate,NADH:oxygen oxidoreductase (3,4-hydroxylating, dechlorinating)
Reaction
- 4-chlorophenylacetate + NADH + H+ + O2 = 3,4-dihydroxyphenylacetate + chloride + NAD+
Cofactor
Comments:
A system, containing a reductase and an iron-sulfur oxygenase, and no independent ferredoxin. Requires Fe2+. Also acts on 4-bromophenyl acetate.
Links to other databases
Enzymes and pathways:
NC-IUBMB
,
BRENDA
,
DIAGRAM
,
ExplorEnz
,
ENZYME@ExPASy
,
KEGG
,
MetaCyc
,
UM-BBD
,
UniPathway
Gene Ontology:
GO:0018622
CAS Registry Number:
105006-00-6
References
-
Purification and some properties of component A of the 4-chlorophenylacetate 3,4-dioxygenase from Pseudomonas species strain CBS.J. Biol. Chem. 261 : 12883-12888 (1986). [PMID: 3745216]
[EC 1.14.12.9 created 1989 as EC 1.13.99.4, transferred 1992 to EC 1.14.12.9]