EC 1.14.12.17 - Nitric oxide dioxygenase

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IntEnz Enzyme Nomenclature
EC 1.14.12.17

Names

Accepted name:
nitric oxide dioxygenase
Other name:
NOD
Systematic name:
nitric oxide,NAD(P)H:oxygen oxidoreductase

Reaction

Cofactors

Comments:

A flavohemoglobin (FAD). It has been proposed that FAD functions as the electron carrier from NADPH to the ferric heme prosthetic group.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0008941
UniProtKB/Swiss-Prot: (47) [show] [UniProt]

References

  1. Gardner, P.R., Costantino, G. and Salzman, A.L.
    Constitutive and adaptive detoxification of nitric oxide in Escherichia coli. Role of nitric-oxide dioxygenase in the protection of aconitase.
    J. Biol. Chem. 273 : 26528-26533 (1998). [PMID: 9756889]
  2. Gardner, P.R., Gardner, A.M., Martin, L.A. and Salzman, A.L.
    Nitric oxide dioxygenase: an enzymic function for flavohemoglobin.
    Proc. Natl. Acad. Sci. USA 95 : 10378-10383 (1998). [PMID: 9724711]

[EC 1.14.12.17 created 2000]