EC - 2-hydroxyquinoline 5,6-dioxygenase

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IntEnz Enzyme Nomenclature


Accepted name:
2-hydroxyquinoline 5,6-dioxygenase
Other names:
2-oxo-1,2-dihydroquinoline 5,6-dioxygenase
quinolin-2-ol 5,6-dioxygenase
quinolin-2(1H)-one 5,6-dioxygenase
Systematic name:
quinolin-2-ol,NADH:oxygen oxidoreductase (5,6-hydroxylating)



3-Methylquinolin-2-ol, quinolin-8-ol and quinolin-2,8-diol are also substrates. Quinolin-2-ols exist largely as their quinolin-2(1H)-one tautomers.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UM-BBD , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0018629
CAS Registry Number: 172399-50-7


  1. Schach, S.B., Tshisuaka, B., Fetzner, S. and Lingens, F.
    Quinoline 2-oxidoreductase and 2-oxo-1,2-dihydroquinoline 5,6-dioxygenase from Comamonas testosteroni 63. The first two enzymes in quinoline and 3-methylquinoline degradation.
    Eur. J. Biochem. 232 : 536-544 (1995). [PMID: 7556204]

[EC created 1999]