EC 1.14.11.56 - L-proline cis-4-hydroxylase

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IntEnz Enzyme Nomenclature
EC 1.14.11.56

Names

Accepted name:
L-proline cis-4-hydroxylase
Systematic name:
L-proline,2-oxoglutarate:oxygen oxidoreductase (cis-4-hydroxylating)

Reaction

Cofactors

Comments:

Requires Fe2+ and ascorbate. The enzyme, isolated from Rhizobium species, only produces cis-4-hydroxy-L-proline (cf. EC 1.14.11.57, L-proline trans-4-hydroxylase).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Hara, R., Kino, K.
    Characterization of novel 2-oxoglutarate dependent dioxygenases converting L-proline to cis-4-hydroxy-L-proline.
    Biochem. Biophys. Res. Commun. 379: 882-886 (2009). [PMID: 19133227]

[EC 1.14.11.56 created 2017]