EC 1.14.11.52 - Validamycin A dioxygenase

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IntEnz Enzyme Nomenclature
EC 1.14.11.52

Names

Accepted name:
validamycin A dioxygenase
Other name:
vldW (gene name)
Systematic name:
validamycin-A,2-oxoglutarate:oxygen oxidoreductase (6'-hydroxylating)

Reaction

Cofactor

Comments:

The enzyme was characterized from the bacterium Streptomyces hygroscopicus subsp. limoneus. Requires Fe2+.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Almabruk, K. H., Asamizu, S., Chang, A., Varghese, S. G., Mahmud, T.
    The ?-ketoglutarate/Fe(II)-dependent dioxygenase VldW is responsible for the formation of validamycin B.
    Chembiochem 13: 2209-2211 (2012). [PMID: 22961651]

[EC 1.14.11.52 created 2016]