IntEnz

EC 1.14.11.17 - Taurine dioxygenase

IntEnz Enzyme Nomenclature
EC 1.14.11.17

Names

Reaction

• 15909 [IUBMB]
  2-oxoglutarate

  2-oxoglutarate

  Name origin: UniProt - CHECKED (C)

  CHEBI:16810

  Formula: C5H4O5
  Charge: -2

  ChEBI compound status: CHECKED (C)

  

  +

  O₂

  O2

  Name origin: UniProt - CHECKED (C)

  CHEBI:15379

  Formula: O2
  Charge: 0

  ChEBI compound status: CHECKED (C)

  

  +

  taurine

  taurine

  Name origin: UniProt - CHECKED (C)

  CHEBI:507393

  Formula: C2H7NO3S
  Charge: 0

  ChEBI compound status: CHECKED (C)

  

  =

  aminoacetaldehyde

  aminoacetaldehyde

  Name origin: UniProt - CHECKED (C)

  CHEBI:58213

  Formula: C2H6NO
  Charge: 1

  ChEBI compound status: CHECKED (C)

  

  +

  CO₂

  CO2

  Name origin: UniProt - CHECKED (C)

  CHEBI:16526

  Formula: CO2
  Charge: 0

  ChEBI compound status: CHECKED (C)

  

  +

  H⁺

  H(+)

  Name origin: UniProt - CHECKED (C)

  CHEBI:15378

  Formula: H
  Charge: 1

  ChEBI compound status: CHECKED (C)

  

  +

  succinate

  succinate

  Name origin: UniProt - CHECKED (C)

  CHEBI:30031

  Formula: C4H4O4
  Charge: -2

  ChEBI compound status: CHECKED (C)

  

  +

  sulfite

  sulfite

  Name origin: UniProt - CHECKED (C)

  CHEBI:17359

  Formula: O3S
  Charge: -2

  ChEBI compound status: CHECKED (C)

  

Cofactors

• L-ascorbate
• Fe²⁺

Comments:

Requires Fe^II. The enzyme from Escherichia coli also acts on pentanesulfonate, 3-(N-morpholino)propanesulfonate and 2-(1,3-dioxoisoindolin-2-yl)ethanesulfonate, but at lower rates.

Links to other databases

References

1. Eichhorn, E., Van Der Poeg, J.R., Kertesz, M.A. and Leisinger, T.
   Characterization of α-ketoglutarate-dependent taurine dioxygenase from Escherichia coli.
   J.Biol. Chem. 272: 23031-23036 (1997). [PMID: 9287300]

[EC 1.14.11.17 created 2000]