EC 1 - Oxidoreductases
EC 1.14 - Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2
EC 1.14.11 - With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
EC 1.14.11.17 - Taurine dioxygenase
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 1.14.11.17
Names
Accepted name:
taurine dioxygenase
Other
names:
2-aminoethanesulfonate dioxygenase
α-ketoglutarate-dependent taurine dioxygenase
α-ketoglutarate-dependent taurine dioxygenase
Systematic name:
taurine, 2-oxoglutarate:oxygen oxidoreductase (sulfite-forming)
Reaction
- taurine + 2-oxoglutarate + O2 = sulfite + aminoacetaldehyde + succinate + CO2
Cofactors
Comments:
Requires FeII. The enzyme from Escherichia coli also acts on pentanesulfonate, 3-(N-morpholino)propanesulfonate and 2-(1,3-dioxoisoindolin-2-yl)ethanesulfonate, but at lower rates.
Links to other databases
Gene Ontology:
GO:0000908
UniProtKB/Swiss-Prot:
References
-
Characterization of α-ketoglutarate-dependent taurine dioxygenase from Escherichia coli.J.Biol. Chem. 272 : 23031-23036 (1997). [PMID: 9287300]
[EC 1.14.11.17 created 2000]