EC 1.14 - Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2

Description

This subclass contains enzymes that act on two hydrogen-donors, and oxygen is incorporated into one or both of them. Sub-subclasses are based on the second donor and the number of oxygen atoms that are incorporated into one or both donors: 2-oxoglutarate is one donor and one atom of oxygen is incorporated into each donor (EC 1.14.11), NADH or NADPH is one donor, and two atoms of oxygen are incorporated into the other donor (EC 1.14.12), NADH or NADPH is one donor, but only one atom of oxygen is incorporated into the other donor (EC 1.14.13). In sub-subclasses EC 1.14.14-1.14.18, one atom of oxygen is incorporated into one donor, the other donor being a reduced flavin or flavoprotein (EC 1.14.14), a reduced iron-sulfur protein (EC 1.14.15), a reduced pteridine (EC 1.14.16), reduced ascorbate (EC 1.14.17), or some other compound (EC 1.14.18). Sub-subclass EC 1.14.19 differs from others in subclass EC 1.14 in that hydrogen atoms removed from the two donors are combined with O2 to form two molecules of water. Sub-subclass EC 1.14.20 has 2-oxoglutarate as one donor, and the other is dehydrogenated. Sub-subclass EC 1.14.21 has NADH or NADPH as one donor, and the other is dehydrogenated. Sub-subclass EC 1.14.99 is for cases where information about the second donor is incomplete.

Contents

EC 1.14.1
With NADH or NADPH as one donor
EC 1.14.2
With ascorbate as one donor
EC 1.14.3
With reduced pteridine as one donor
EC 1.14.11
With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
EC 1.14.12
With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor
EC 1.14.13
With NADH or NADPH as one donor, and incorporation of one atom of oxygen
EC 1.14.14
With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
EC 1.14.15
With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
EC 1.14.16
With reduced pteridine as one donor, and incorporation of one atom of oxygen
EC 1.14.17
With reduced ascorbate as one donor, and incorporation of one atom of oxygen
EC 1.14.18
With another compound as one donor, and incorporation of one atom of oxygen
EC 1.14.19
With oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
EC 1.14.20
With 2-oxoglutarate as one donor, and the other dehydrogenated
EC 1.14.21
With NADH or NADPH as one donor, and the other dehydrogenated
EC 1.14.99
Miscellaneous