EC 1.13.12.4 - Lactate 2-monooxygenase

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IntEnz Enzyme Nomenclature
EC 1.13.12.4

Names

Accepted name:
lactate 2-monooxygenase
Other names:
L-lactate monooxygenase
L-lactate-2-monooxygenase
lactate monooxygenase
lactate oxidase
lactate oxidative decarboxylase
lactate oxygenase
lactic oxidase
lactic oxygenase
Systematic name:
(S)-lactate:oxygen 2-oxidoreductase (decarboxylating)

Reaction

Cofactor

Comments:

A flavoprotein (FMN). Formerly EC 1.1.3.2.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00482
Structural data: CSA , EC2PDB
Gene Ontology: GO:0050040
CAS Registry Number: 9028-72-2
UniProtKB/Swiss-Prot:

References

  1. Hayaishi, O. and Sutton, W.B.
    Enzymatic oxygen fixation into acetate concomitant with the enzymatic decarboxylation of L-lactate.
    J. Am. Chem. Soc. 79: 4809-4810 (1957).
  2. Sutton, W.B.
    Mechanism of action and crystalization of lactic oxidative decarboxylase from Mycobacterium phlei.
    J. Biol. Chem. 226: 395-405 (1957).

[EC 1.13.12.4 created 1961 as EC 1.1.3.2, transferred 1972 to EC 1.13.12.4]