EC - Tryptophan 2-monooxygenase

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IntEnz Enzyme Nomenclature


Accepted name:
tryptophan 2-monooxygenase
Systematic name:
L-tryptophan:oxygen 2-oxidoreductase (decarboxylating)


Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0050361
CAS Registry Number: 37256-65-8


  1. Kosuge, T., Heskett, M.G. and Wilson, E.E.
    Microbial synthesis and degradation of indole-3-acetic acid. I. The conversion of L-tryptophan to indole-3-acetamide by an enzyme system from Pseudomonas savastanoi.
    J. Biol. Chem. 241 : 3738-3744 (1966). [PMID: 5916389]
  2. Kuo, T.T. and Kosuge, T.
    Factors influencing the production and further metabolism of indole-3-acetic acid by Pseudomonas savastanoi.
    J. Gen. Appl. Microbiol. 15 : 51-63 (1969).
  3. Emanuele, J. J., Fitzpatrick, P. F.
    Mechanistic studies of the flavoprotein tryptophan 2-monooxygenase. 1. Kinetic mechanism.
    Biochemistry 34 : 3710-3715 (1995). [PMID: 7893667]

[EC created 1972]