EC 1.13.11.30 - Stizolobinate synthase

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IntEnz Enzyme Nomenclature
EC 1.13.11.30

Names

Accepted name:
stizolobinate synthase
Systematic name:
3,4-dihydroxy-L-phenylalanine:oxygen 2,3-oxidoreductase (recyclizing)

Reaction

Cofactor

Comments:

The intermediate product undergoes ring closure and oxidation, with NAD(P)+ as acceptor, to stizolobinic acid. The enzyme requires Zn2+.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0050298
CAS Registry Number: 65979-38-6

References

  1. Saito, K. and Komamine, A.
    Biosynthesis of stizolobinic acid and stizolobic acid in higher plants. An enzyme system(s) catalyzing the conversion of dihydroxyphenylalanine into stizolobinic acid and stizolobic acid from etiolated seedlings of Stizolobium hassjoo.
    Eur. J. Biochem. 68: 237-243 (1976). [PMID: 9285]
  2. Saito, K. and Komamine, A.
    Biosynthesis of stizolobinic acid and stizolobic acid in higher plants.
    Eur. J. Biochem. 82: 385-392 (1978). [PMID: 624278]

[EC 1.13.11.30 created 1978]