EC 1.12.1.5 - Hydrogen dehydrogenase [NAD(P)+]

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IntEnz Enzyme Nomenclature
EC 1.12.1.5

Names

Accepted name:
hydrogen dehydrogenase [NAD(P)+]
Other name:
hydrogenase II [ambiguous]
Systematic name:
hydrogen:NAD(P)+ oxidoreductase

Reaction

Cofactors

Comments:

A nickel, iron, iron-sulfur protein. The enzyme from the archaeon Pyrococcus furiosus is part of a heterotetrameric complex where the α and δ subunits function as a hydrogenase while the β and γ subunits function as sulfur reductase (EC 1.12.98.4, sulfhydrogenase). Different from EC 1.12.1.3, hydrogen dehydrogenase (NADP+).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Ma, K., Weiss, R., Adams, M. W.
    Characterization of hydrogenase II from the hyperthermophilic archaeon Pyrococcus furiosus and assessment of its role in sulfur reduction.
    J. Bacteriol. 182 : 1864-1871 (2000). [PMID: 10714990]

[EC 1.12.1.5 created 2013]