EC 1.10.3.16 - Dihydrophenazinedicarboxylate synthase

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IntEnz Enzyme Nomenclature
EC 1.10.3.16

Names

Accepted name:
dihydrophenazinedicarboxylate synthase
Other name:
phzG (gene name)
Systematic name:
1,4,5a,6,9,10a-hexahydrophenazine-1,6-dicarboxylate:oxygen oxidoreductase

Reactions

Cofactor

Comments:

Requires FMN. The enzyme, isolated from the bacteria Pseudomonas fluorescens 2-79 and Burkholderia lata 383, is involved in biosynthesis of the reduced forms of phenazine, phenazine-1-carboxylate, and phenazine-1,6-dicarboxylate, where it catalyses multiple reactions.

The enzyme, isolated from the bacteria Pseudomonas fluorescens 2-79 and Burkholderia lata 383, is involved in biosynthesis of the reduced forms of phenazine, phenazine-1-carboxylate, and phenazine-1,6-dicarboxylate, where it catalyses multiple reactions.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB

References

  1. Xu, N., Ahuja, E. G., Janning, P., Mavrodi, D. V., Thomashow, L. S., Blankenfeldt, W.
    Trapped intermediates in crystals of the FMN-dependent oxidase PhzG provide insight into the final steps of phenazine biosynthesis.
    Acta Crystallogr. D Biol. Crystallogr. 69: 1403-1413 (2013). [PMID: 23897464]

[EC 1.10.3.16 created 2016]